The aim of this study was to determine the presence of tetracycline resistance genes and the int gene in enterococcus isolates from broilers carrying the erm b gene, as an aid in assessing the potential risk of poultry enterococci acting as a pool of resistance genes.
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Mammalian cells are less vulnerable to the effect of tetracyclines, despite the fact that tetracycline binds to the small ribosomal subunit of both prokaryotes and eukaryotes 30s and 40s, respectively .
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Previous studies identified two conserved tyrosines within loop iii of tetm as being important for tetracycline resistance 3, 19, 20 .
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, vestibular reactions occur more frequently with minocycline than with other currently available tetracyclines.
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While this is not a problem in those with normal renal function, in patients with significantly impaired function, higher serum levels of tetracycline may lead to azotemia, hyperphosphatemia, and acidosis.
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A when penicillin is contraindicated, tetracyclines are alternative drugs in the treatment of infections caused by the cited microorganisms.
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